RUV-III-C

Variations of Remove Unwanted Variation-III (RUV-III) known as RUV-III-C (RUV-III Complete). RUV-III performs normalisation using negative control variables and replication. RUV-III-C extends this method to cases where the data contains missing values, by applying RUV-III to complete subsets of the data. Originally designed for SWATH-MS proteomics datasets. Poulos et al. (2020) .

'Rcpp'-Based Helper Functions to Pass 'Int64' and 'nanotime' Values Between 'R' and 'C++'

'Int64' values can be created and accessed via the 'bit64' package and its 'integer64' class which package the 'int64' representation cleverly into a 'double'. The 'nanotime' packages builds on this to support nanosecond-resolution timestamps. This packages helps conversions between 'R' and 'C++' via several helper functions provided via a single header file. A complete example client package is included as an illustration.

Interpolation From C

Simple interpolation methods designed to be used from C code. Supports constant, linear and spline interpolation. An R wrapper is included but this package is primarily designed to be used from C code using 'LinkingTo'. The spline calculations are classical cubic interpolation, e.g., Forsythe, Malcolm and Moler (1977) .

A Collection of Efficient and Extremely Fast R Functions

A collection of fast (utility) functions for data analysis. Column and row wise means, medians, variances, minimums, maximums, many t, F and G-square tests, many regressions (normal, logistic, Poisson), are some of the many fast functions. References: a) Tsagris M., Papadakis M. (2018). Taking R to its limits: 70+ tips. PeerJ Preprints 6:e26605v1 . b) Tsagris M. and Papadakis M. (2018). Forward regression in R: from the extreme slow to the extreme fast. Journal of Data Science, 16(4): 771--780. . c) Chatzipantsiou C., Dimitriadis M., Papadakis M. and Tsagris M. (2020). Extremely Efficient Permutation and Bootstrap Hypothesis Tests Using Hypothesis Tests Using R. Journal of Modern Applied Statistical Methods, 18(2), eP2898. . d) Tsagris M., Papadakis M., Alenazi A. and Alzeley O. (2024). Computationally Efficient Outlier Detection for High-Dimensional Data Using the MDP Algorithm. Computation, 12(9): 185. . e) Tsagris M. and Papadakis M. (2025). Fast and light-weight energy statistics using the R package Rfast. .

Multiple Precision Arithmetic

Multiple Precision Arithmetic (big integers and rationals, prime number tests, matrix computation), "arithmetic without limitations" using the C library GMP (GNU Multiple Precision Arithmetic).

Regression Spline Functions and Classes

Constructs basis functions of B-splines, M-splines, I-splines, convex splines (C-splines), periodic splines, natural cubic splines, generalized Bernstein polynomials, their derivatives, and integrals (except C-splines) by closed-form recursive formulas. It also contains a C++ head-only library integrated with Rcpp. See Wang and Yan (2021) for details.

Markov Chain Monte Carlo (MCMC) Package

Contains functions to perform Bayesian inference using posterior simulation for a number of statistical models. Most simulation is done in compiled C++ written in the Scythe Statistical Library Version 1.0.3. All models return 'coda' mcmc objects that can then be summarized using the 'coda' package. Some useful utility functions such as density functions, pseudo-random number generators for statistical distributions, a general purpose Metropolis sampling algorithm, and tools for visualization are provided.

Tidy C++ Header-Only Definitions for Parts of the C API of R

Core parts of the C API of R are wrapped in a C++ namespace via a set of inline functions giving a tidier representation of the underlying data structures and functionality using a header-only implementation without additional dependencies.

C/C++ Source Code to Trigger Address and Undefined Behaviour Sanitizers

Recent gcc and clang compiler versions provide functionality to test for memory violations and other undefined behaviour; this is often referred to as "Address Sanitizer" (or 'ASAN') and "Undefined Behaviour Sanitizer" ('UBSAN'). The Writing R Extension manual describes this in some detail in Section 4.3 title "Checking Memory Access". This feature has to be enabled in the corresponding binary, eg in R, which is somewhat involved as it also required a current compiler toolchain which is not yet widely available, or in the case of Windows, not available at all (via the common Rtools mechanism). As an alternative, pre-built Docker containers such as the Rocker container 'r-devel-san' or the multi-purpose container 'r-debug' can be used. This package then provides a means of testing the compiler setup as the known code failures provides in the sample code here should be detected correctly, whereas a default build of R will let the package pass. The code samples are based on the examples from the Address Sanitizer Wiki at < https://github.com/google/sanitizers/wiki>.

'Rapidjson' C++ Header Files

Provides JSON parsing capability through the 'Rapidjson' 'C++' header-only library.