Multiple Imputation for Informative Censoring

Multiple Imputation for Informative Censoring. This package implements two methods. Gamma Imputation from Jackson et al. (2014) and Risk Score Imputation from Hsu et al. (2009) .


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Multiple Imputation for Informative Censoring

This R package implement two methods for multiple imputation of survival data.

  • Gamma imputation from Jackson et al. [1]
  • Risk score imputation from Hsu et al. [2]

Contributor (alphabetical order)

Bartlett, Jonathan (maintainer); Burkoff, Nikolas; Jackson, Dan; Jones, Edmund; Law, Martin; Metcalfe, Paul; Ruau, David;

Installation

To install the development version from GitHub:

install.packages("devtools")
# We spent a lot of time developing the vignettes. We recommend the read but 
# building them from source takes some time
devtools::install_github("scientific-computing-solutions/InformativeCensoring", 
                         build_vignettes = TRUE)

Gamma imputation (Jackson 2014)

The Gamma imputation method implementation was developed in collaboration between AstraZeneca, the MRC Biostatistics Unit and the University of Cambridge.

This implementation was validated to the best of our effort following good coding practice and thorough user testing.

Risk Score Imputation (Hsu 2009)

We implemented the method described in Chiu-Hsieh Hsu and Jeremy Taylor (2009) following the publication.

This implementation was validated to the best of our effort following good coding practice and thorough user testing.

[1] Dan Jackson, Ian White, Shaun Seaman, Hannah Evans, Kathy Baisley, and James Carpenter. Relaxing the independent censoring assumption in the Cox proportional hazards model using multiple imputation. Statistics in Medicine, 33(27):4681–4694, 2014.

[2] Chiu-Hsieh Hsu and Jeremy MG Taylor. Nonparametric comparison of two survival functions with dependent censoring via nonparametric multiple imputation. Statistics in Medicine, 28(3):462–475, 2009.

News

Reference manual

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install.packages("InformativeCensoring")

0.3.4 by Jonathan Bartlett, 2 years ago


https://github.com/scientific-computing-solutions/InformativeCensoring


Browse source code at https://github.com/cran/InformativeCensoring


Authors: David Ruau [aut], Nikolas Burkoff [aut], Jonathan Bartlett [aut, cre], Dan Jackson [aut], Edmund Jones [aut], Martin Law [aut], Paul Metcalfe [aut]


Documentation:   PDF Manual  


Task views: Survival Analysis, Clinical Trial Design, Monitoring, and Analysis


GPL (>= 2) | file LICENSE license


Imports boot, dplyr, parallel

Depends on survival

Suggests knitr, testthat


See at CRAN