Seamless Dose Escalation/Expansion with Adaptive Randomization Scheme

A seamless design that combines phase I dose escalation based on toxicity with phase II dose expansion and dose comparison based on efficacy.

Reference manual

install.packages("SEARS")

0.1.0 by Chia-Wei Hsu, 3 years ago

Browse source code at https://github.com/cran/SEARS

Authors: Chia-Wei Hsu [aut, cre] , Haitao Pan [aut]

Documentation: PDF Manual

GPL-2 license

Depends on BOIN

Suggests knitr, rmarkdown