Detection of Kataegis

Kataegis is a localized hypermutation occurring when a region is enriched in somatic SNVs. Kataegis can result from multiple cytosine deaminations catalyzed by the AID/APOBEC family of proteins. This package contains functions to detect kataegis from SNVs in BED format. This package reports two scores per kataegic event, a hypermutation score and an APOBEC mediated kataegic score. Yousif, F. et al.; The Origins and Consequences of Localized and Global Somatic Hypermutation; Biorxiv 2018 .


Reference manual

It appears you don't have a PDF plugin for this browser. You can click here to download the reference manual.

install.packages("SeqKat")

0.0.9 by Paul C. Boutros, 8 months ago


https://github.com/TheBoutrosLab/package-SeqKat


Report a bug at https://github.com/TheBoutrosLab/package-SeqKat/issues


Browse source code at https://github.com/cran/SeqKat


Authors: Fouad Yousif [aut] , Xihui Lin [aut] , Fan Fan [aut] , Christopher Lalansingh [aut] , John Macdonald [aut] , Paul C. Boutros [cre]


Documentation:   PDF Manual  


GPL (>= 2) license


Imports Rcpp

Depends on foreach, doParallel

Suggests testthat, doMC, rmarkdown, knitr

Linking to Rcpp


See at CRAN