Clinical Trial Design and Data Analysis Functions

Utilities to make your clinical collaborations easier if not fun. It contains functions for designing studies such as Simon 2-stage and group sequential designs and for data analysis such as Jonckheere-Terpstra test and estimating survival quantiles.


Reference manual

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1.0.15 by Venkatraman E. Seshan, a year ago

Browse source code at

Authors: Venkatraman E. Seshan

Documentation:   PDF Manual  

Task views: Clinical Trial Design, Monitoring, and Analysis, Survival Analysis

GPL (>= 2) license

Imports mvtnorm

Depends on graphics, stats

Suggests survival

Imported by NPMOD, StatCharrms, hctrial, ph2mult.

Depended on by EurosarcBayes, OptInterim, binseqtest, gMWT, ph2hetero.

Suggested by ADCT, RcmdrPlugin.EZR, ph2bye.

See at CRAN