Design and Analysis of Non-Inferiority Trials

Provides tools to help the design and analysis of resilient non-inferiority trials. These include functions for sample size calculations and analyses of trials, with either a risk difference, risk ratio or arc-sine difference margin, and a function to run simulations to design a trial with the methods described in Quartagno et al. (2019) .


Reference manual

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install.packages("dani")

0.1-1 by Matteo Quartagno, 7 years ago


Browse source code at https://github.com/cran/dani


Authors: Matteo Quartagno


Documentation:   PDF Manual  


GPL-2 license


Depends on Epi


See at CRAN