Estimated Glomerular Filtration Rate (eGFR) Calculators

A comprehensive, vectorised toolkit for estimating glomerular filtration rate (eGFR) and creatinine clearance from serum creatinine, cystatin C, or both. Implements adult, paediatric, and neonatal equations, including the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations (2009, 2012, 2021), the Modification of Diet in Renal Disease (MDRD) Study equation, Cockcroft-Gault, the European Kidney Function Consortium (EKFC) equations, the Full Age Spectrum (FAS) equations, the Lund-Malmoe equations, the Berlin Initiative Study (BIS) equations, the Schwartz bedside equation, the Chronic Kidney Disease in Children Under 25 (CKiD U25) equations, the Caucasian, Asian, Paediatric, and Adult (CAPA) cystatin C equation, and a neonatal equation. Helpers for body surface area, chronic kidney disease (CKD) staging following the Kidney Disease: Improving Global Outcomes (KDIGO) guideline, and unit conversions are included. Methods are described in Levey et al. (2009) , Inker et al. (2021) , and Pottel et al. (2021) . Inspired by the 'kidney.epi' package.

egfr

egfr is a vectorised R toolkit for estimating glomerular filtration rate (eGFR) and creatinine clearance from serum creatinine, cystatin C, or both. It implements 19 validated adult, paediatric, and neonatal equations, plus helpers for body surface area, KDIGO CKD staging, and unit conversion.

The package is inspired by the kidney.epi package and was ported from the equation set used by eGFR.app.

These equations are screening tools and are not a substitute for measured GFR or clinical judgement.

Installation

Install the released version from R-universe:

install.packages("egfr", repos = "https://mhovd.r-universe.dev")

Or install the development version from GitHub:

# install.packages("remotes")
remotes::install_github("mhovd/egfr")

Quick start

library(egfr)

# CKD-EPI 2021 creatinine (race-free) — recommended for adults
egfr_ckdepi_cr_2021(creatinine = 1.0, age = 50, sex = "female")
#> 68.6

# Fully vectorised: pass vectors for any argument
egfr_ckdepi_cr_2021(
  creatinine = c(0.8, 1.2, 1.5),
  age        = c(40, 65, 72),
  sex        = c("female", "male", "female")
)

# Units: supply creatinine in umol/L instead of mg/dL
egfr_ckdepi_cr_2021(88.4, 50, "female", creatinine_units = "umol/l")

# Classify the result into a KDIGO stage
ckd_stage(egfr_ckdepi_cr_2021(1.0, 50, "female"))
#> "G2"

Available equations

Adult

Paediatric & neonatal

Helpers

Conventions

• All egfr_*() functions return unrounded values in mL/min/1.73m^2, except egfr_cockcroft_gault(), which returns creatinine clearance in mL/min.
• Creatinine defaults to mg/dL; pass creatinine_units = "umol/l" to use SI units. Height defaults to cm.
• Sex labels default to "male"/"female" and can be customised via label_sex_male / label_sex_female.

License

MIT (c) 2026 Markus Hovd.