Noncompartmental Analysis for Pharmacokinetic Report

Conduct a noncompartmental analysis with industrial strength. Some features are 1) CDISC SDTM terms 2) Automatic or manual slope selection 3) Supporting both 'linear-up linear-down' and 'linear-up log-down' method 4) Interval(partial) AUCs with 'linear' or 'log' interpolation method 5) Steady-state analysis over the dosing interval (AUCTAU, CAVG, CL and Vz from AUCTAU) 6) Produce pdf, rtf, text report files. 7) Produce Installation and Operational Qualification (IQ/OQ) reports in pdf. After installation, qualify the package in your own environment: run pdfIQ() for Installation Qualification and pdfOQ() for Operational Qualification. Run writeMD5() once after installation so the IQ file-integrity check passes. To approve a report, sign it digitally in Adobe Acrobat Reader (generate with sigField=TRUE, or run addSigField(), to add click-to-sign fields), instead of printing and scanning; or use signPDF()/verifyPDF() for a scriptable signature. * Reference: Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016. (ISBN:9198299107).


Reference manual

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install.packages("ncar")

0.7.2 by Kyun-Seop Bae, 17 days ago


https://cran.r-project.org/package=ncar


Browse source code at https://github.com/cran/ncar


Authors: Kyun-Seop Bae [aut, cre] , Michael E. Schaffer [ctb, cph] (Original author of the 'rtf' functions vendored in R/rtf_utils.R)


Documentation:   PDF Manual  


GPL-3 license


Imports NonCompart, R.oo, R.methodsS3, tools

Suggests openssl


See at CRAN