Higher Criticism Tests for Non-Proportional Hazard Deviations

Implements omnibus tests for comparing two right-censored survival samples that are powerful against sparse departures from equal hazards, where the hazard difference is concentrated in a small and a priori unknown subset of the follow-up. Exact hypergeometric p-values are computed for each time interval and aggregated with the Higher Criticism statistic of Donoho and Jin (2004) , or alternatively with the Berk-Jones, Fisher or minimum-p statistics. Global p-values are obtained by permuting group labels, and the intervals driving a detection can be recovered for diagnostic plotting. Tests accept either two samples as vectors or the usual survival formula. The method is described in Kipnis, Galili and Yakhini (2026) , and the companion application note is Kipnis, Galili and Yakhini (2026) .