Analysis of Data from a Crossover Design with GEE

Analyze data from a crossover design using generalized estimation equations (GEE), including carryover effects and various correlation structures based on the Kronecker product. It contains functions for semiparametric estimates of carry-over effects in repeated measures and allows estimation of complex carry-over effects. Related work includes: a) Cruz N.A., Melo O.O., Martinez C.A. (2023). "CrossCarry: An R package for the analysis of data from a crossover design with GEE". . b) Cruz N.A., Melo O.O., Martinez C.A. (2023). "A correlation structure for the analysis of Gaussian and non-Gaussian responses in crossover experimental designs with repeated measures". and c) Cruz N.A., Melo O.O., Martinez C.A. (2023). "Semiparametric generalized estimating equations for repeated measurements in cross-over designs". .


Reference manual

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install.packages("CrossCarry")

1.2.0 by Nelson Alirio Cruz Gutierrez, 10 months ago


Browse source code at https://github.com/cran/CrossCarry


Authors: Nelson Alirio Cruz Gutierrez [aut, cre, cph] , Oscar Orlando Melo [aut] , Carlos Alberto Martinez [aut] , Ricardo Alberich Marti [aut]


Documentation:   PDF Manual  


GPL (>= 3) license


Imports dplyr, gee, ggplot2, splines, stats, MASS

Suggests testthat


See at CRAN