Estimate the Gene Expression Levels and Component Proportions of the Normal, Stroma (Immune) and Tumor Components of Bulk Tumor Samples

Model cell type heterogeneity of bulk renal cell carcinoma. The observed gene expression in bulk tumor sample is modeled by a log-normal distribution with the location parameter structured as a linear combination of the component-specific gene expressions.



  • Experimental version

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1.0.0 by Tao Wang, a month ago

Browse source code at

Authors: Tao Wang

Documentation:   PDF Manual  

GPL-2 license

Depends on gtools, matrixStats

See at CRAN