Design and Analysis of Dose-Finding Studies

Implements a methodology for the design and analysis of dose-response studies that combines aspects of multiple comparison procedures and modeling approaches (Bretz, Pinheiro and Branson, 2005, Biometrics 61, 738-748, ). The package provides tools for the analysis of dose finding trials as well as a variety of tools necessary to plan a trial to be conducted with the MCP-Mod methodology. Please note: The 'MCPMod' package will not be further developed, all future development of the MCP-Mod methodology will be done in the 'DoseFinding' R-package.


News

  • The package now includes a vignette describing methodology and package. The package R source code is identical to versions 0.2-1 and 0.2-2.
  • There will be an article in Journal of Statistical Software describing the package. This paper refers to version 0.2-1 of the package.
  • First release.

Reference manual

It appears you don't have a PDF plugin for this browser. You can click here to download the reference manual.

install.packages("MCPMod")

1.0-10 by Bjoern Bornkamp, 18 days ago


Browse source code at https://github.com/cran/MCPMod


Authors: Bjoern Bornkamp, Jose Pinheiro and Frank Bretz


Documentation:   PDF Manual  


Task views: Clinical Trial Design, Monitoring, and Analysis


GPL-3 license


Depends on mvtnorm, lattice


See at CRAN