Tools for Analysing N-Glycan Data

Useful utilities in N-glycan data analysis. This package tries to fill the gap in N-glycan data analysis by providing easy to use functions for basic operations on data (see https://en.wikipedia.org/wiki/Glycomics for more details on Glycomics). At the moment glycanr is mostly oriented to data obtained by UPLC and LCMS analysis of Plasma and IgG glycome.


Glycomics is rapidly emerging field in high-throughput biology that aims to systematically study glycan structures of a given protein, cell type or organic system. As within other high-throughput methods in biology (microarrays, metabolomics, proteomics), accuracy of high-throughput methods is highly affected by complicated experimental procedures leading to differences between replicates and the existence of batch effects, among others.

This package tries to fill the gap in N-glycan data analysis by providing easy to use functions for glycomics analysis. At the moment it is mostly oriented to data obtained by UPLC and LCMS analysis of Plasma and IgG glycome.

For a broader introduction take a look at "Introduction" vignette.

install.packages('glycanr')

The package can be installed for example with devtools package.

install.packages('devtools')

Load the devtools package.

library(devtools)

Install the package.

install_github('iugrina/glycanr', build_vignette=TRUE)

News

glycanr 0.3.0

  • travis conf added (GitHub related)
  • updated README
  • improved DESCRIPTION by adding Suggests
  • improved documentation
  • unit tests for normalization functions added
  • new normalization functions added
  • improved list of authors
  • tanorm function now expects data frame in long format
  • glyco.outliers now expects data frame in long format
  • added example data (raw and normalized) for IgG UPLC measurements

glycanr 0.2.0

  • released on CRAN
  • a lot of changes from previous versions

Reference manual

It appears you don't have a PDF plugin for this browser. You can click here to download the reference manual.

install.packages("glycanr")

0.3.0 by Ivo Ugrina, a year ago


https://github.com/iugrina/glycanr


Report a bug at https://github.com/iugrina/glycanr/issues


Browse source code at https://github.com/cran/glycanr


Authors: Ivo Ugrina [aut, cre, cph], Lucija Klaric [aut], Frano Vuckovic [aut]


Documentation:   PDF Manual  


MIT + file LICENSE license


Imports ggplot2, tidyr, dplyr, coin

Suggests knitr, preprocessCore, testthat


See at CRAN