Global Sensitivity Analysis in Pharmacokinetic Modeling

Applying the global sensitivity analysis workflow to investigate the parameter uncertainty and sensitivity in pharmacokinetic (PK) models, especially the physiologically-based pharmacokinetic (PBPK) model with multivariate outputs. The package also provide some functions to check the sensitivity measures and its convergence of model parameters.


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install.packages("pksensi")

1.0.1 by Nan-Hung Hsieh, 21 days ago


https://github.com/nanhung/pksensi, https://nanhung.rbind.io/pksensi


Report a bug at https://github.com/nanhung/pksensi/issues


Browse source code at https://github.com/cran/pksensi


Authors: Nan-Hung Hsieh [aut, cre] , Brad Reisfeld [aut] , Weihsueh A. Chiu [aut]


Documentation:   PDF Manual  


GPL-3 | file LICENSE license


Imports ggplot2, data.table, deSolve, dplyr, getPass, magrittr, reshape

Suggests knitr, rmarkdown, testthat, viridis


See at CRAN