Biochemically Intuitive Generalized Loewe Model

Response surface methods for drug synergy analysis. Available methods include generalized and classical Loewe formulations as well as Highest Single Agent methodology. Response surfaces can be plotted in an interactive 3-D plot and formal statistical tests for presence of synergistic effects are available.


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1.1.0 by Maxim Nazarov, 2 months ago

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Authors: Heather Turner, Annelies Tourny, Olivier Thas, Maxim Nazarov, Rytis Bagdziunas

Documentation:   PDF Manual  

GPL-3 license

Imports ggplot2, MASS, methods, minpack.lm, numDeriv, parallel, progress, rgl, robustbase, scales

Suggests knitr, testthat, shiny, DT

See at CRAN