Biochemically Intuitive Generalized Loewe Model

Response surface methods for drug synergy analysis. Available methods include generalized and classical Loewe formulations as well as Highest Single Agent methodology. Response surfaces can be plotted in an interactive 3-D plot and formal statistical tests for presence of synergistic effects are available.


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install.packages("BIGL")

1.0.1 by Rytis Bagdziunas, 3 months ago


https://github.com/openanalytics/BIGL


Report a bug at https://github.com/openanalytics/BIGL/issues


Browse source code at https://github.com/cran/BIGL


Authors: Heather Turner, Annelies Tourny, Olivier Thas, Maxim Nazarov, Rytis Bagdziunas


Documentation:   PDF Manual  


GPL-3 license


Imports ggplot2, MASS, methods, minpack.lm, numDeriv, parallel, progress, rgl, robustbase, scales

Suggests knitr, testthat, shiny, DT


See at CRAN