ROBust INference for Covariate Adjustment in Randomized Clinical Trials

Performs robust estimation and inference when using covariate adjustment and/or covariate-adaptive randomization in randomized controlled trials. This package is trimmed to reduce the dependencies and validated to be used across industry. See "FDA's final guidance on covariate adjustment"< https://www.regulations.gov/docket/FDA-2019-D-0934>, Tsiatis (2008) , Bugni et al. (2018) , Ye, Shao, Yi, and Zhao (2023), Ye, Shao, and Yi (2022), Rosenblum and van der Laan (2010), Wang et al. (2021), Ye, Bannick, Yi, and Shao (2023), and Bannick, Shao, Liu, Du, Yi, and Ye (2024).

Reference manual

install.packages("RobinCar2")

0.2.4 by Liming Li, 2 months ago

https://github.com/openpharma/RobinCar2/

Report a bug at https://github.com/openpharma/RobinCar2/issues

Browse source code at https://github.com/cran/RobinCar2

Authors: Liming Li [aut, cre] , Marlena Bannick [aut] , Daniel Sabanes Bove [aut] (ORCID: , Dong Xi [aut] , Ting Ye [aut] , Yanyao Yi [aut] , Gregory Chen [ctb] , Gilead Sciences , Inc. [cph, fnd] , F. Hoffmann-La Roche AG [cph, fnd] , Merck Sharp & Dohme , Inc. [cph, fnd] , AstraZeneca plc [cph, fnd] , Eli Lilly and Company [cph, fnd] , Novartis Pharma AG [cph, fnd] , The University of Washington [cph, fnd]

Documentation: PDF Manual

Apache License 2.0 license

Imports checkmate, numDeriv, MASS, sandwich, stats, survival, utils

Suggests knitr, rmarkdown, speff2trial, testthat

See at CRAN

RobinCar2

ROBust INference for Covariate Adjustment in Randomized Clinical Trials

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