Spatial Component Analysis for Spatial Sequencing Data

Spatial components offer tools for dimension reduction and spatially variable gene detection for high dimensional spatial transcriptomics data. Construction of a projection onto low-dimensional feature space of spatially dependent metagenes offers pre-processing to clustering, testing for spatial variability and denoising of spatial expression patterns. For more details, see Koehler et al. (2026) .


Reference manual

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install.packages("SPACO")

1.0.3 by David Köhler, a month ago


Browse source code at https://github.com/cran/SPACO


Authors: David Köhler [aut, cre] (ORCID:


Documentation:   PDF Manual  


MIT + file LICENSE license


Imports ggplot2, Seurat, tibble, ggforce, methods, rARPACK, tidyr, mgcv, scales, Matrix

Suggests testthat

Linking to Rcpp, RcppEigen


See at CRAN