Simulate and Evaluate Time Series for Environmental Epidemiology

Provides functions to create simulated time series of environmental exposures (e.g., temperature, air pollution) and health outcomes for use in power analysis and simulation studies in environmental epidemiology. This package also provides functions to evaluate the results of simulation studies based on these simulated time series. This work was supported by a grant from the National Institute of Environmental Health Sciences (R00ES022631) and a fellowship from the Colorado State University Programs for Research and Scholarly Excellence.

Kidney-Related Functions for Clinical and Epidemiological Research

Contains kidney care oriented functions. Current version contains functions for calculation of: - Estimated glomerular filtration rate by CKD-EPI (2021 and 2009), MDRD, CKiD, FAS, EKFC, etc. - Kidney Donor Risk Index and Kidney Donor Profile Index for kidney transplant donors. - Citation: Bikbov B. kidney.epi: Kidney-Related Functions for Clinical and Epidemiological Research. Scientific-Tools.Org, < https://Scientific-Tools.Org>. .

G-Computation to Estimate Interpretable Epidemiological Effects

Estimates flexible epidemiological effect measures including both differences and ratios using the parametric G-formula developed as an alternative to inverse probability weighting. It is useful for estimating the impact of interventions in the presence of treatment-confounder-feedback. G-computation was originally described by Robbins (1986) and has been described in detail by Ahern, Hubbard, and Galea (2009) ; Snowden, Rose, and Mortimer (2011) ; and Westreich et al. (2012) .

Record Linkage and Epidemiological Case Definitions in 'R'

An R package for iterative and batched record linkage, and applying epidemiological case definitions. 'diyar' can be used for deterministic and probabilistic record linkage, or multistage record linkage combining both approaches. It features the implementation of nested match criteria, and mechanisms to address missing data and conflicting matches during stepwise record linkage. Case definitions are implemented by assigning records to groups based on match criteria such as person or place, and overlapping time or duration of events e.g. sample collection dates or periods of hospital stays. Matching records are assigned a unique group ID. Index and duplicate records are removed or further analyses as required.

Basic Quality Data Assurance for Epidemiological Research

With the provision of several tools and templates the MOSAIC project (DFG-Grant Number HO 1937/2-1) supports the implementation of a central data management in epidemiological research projects. The 'MOQA' package enables epidemiologists with none or low experience in R to generate basic data quality reports for a wide range of application scenarios. See < https://mosaic-greifswald.de/> for more information. Please read and cite the corresponding open access publication (using the former package-name) in METHODS OF INFORMATION IN MEDICINE by M. Bialke, H. Rau, T. Schwaneberg, R. Walk, T. Bahls and W. Hoffmann (2017) . < https://methods.schattauer.de/en/contents/most-recent-articles/issue/2483/issue/special/manuscript/27573/show.html>.

Baseline Nowcasting for Right-Truncated Epidemiological Data

Nowcasting right-truncated epidemiological data is critical for timely public health decision-making, as reporting delays can create misleading impressions of declining trends in recent data. This package provides nowcasting methods based on using empirical delay distributions and uncertainty from past performance. It is also designed to be used as a baseline method for developers of new nowcasting methods. For more details on the performance of the method(s) in this package applied to case studies of COVID-19 and norovirus, see our recent paper at < https://wellcomeopenresearch.org/articles/10-614>. The package supports standard data frame inputs with reference date, report date, and count columns, as well as the direct use of reporting triangles, and is compatible with 'epinowcast' objects. Alongside an opinionated default workflow, it has a low-level pipe-friendly modular interface, allowing context-specific workflows. It can accommodate a wide spectrum of reporting schedules, including mixed patterns of reference and reporting (daily-weekly, weekly-daily). It also supports sharing delay distributions and uncertainty estimates between strata, as well as custom uncertainty models and delay estimation methods.

Epidemiology Data Dictionaries and Random Data Generators

The 'R4EPIs' project < https://r4epi.github.io/sitrep/> seeks to provide a set of standardized tools for analysis of outbreak and survey data in humanitarian aid settings. This package currently provides standardized data dictionaries from Medecins Sans Frontieres Operational Centre Amsterdam for outbreak scenarios (Acute Jaundice Syndrome, Cholera, Diphtheria, Measles, Meningitis) and surveys (Retrospective mortality and access to care, Malnutrition, Vaccination coverage and Event Based Surveillance) - as described in the following < https://scienceportal.msf.org/assets/standardised-mortality-surveys?utm_source=chatgpt.com>. In addition, a data generator from these dictionaries is provided. It is also possible to read in any Open Data Kit format data dictionary.

Interface to 'episensr' for Sensitivity Analysis of Epidemiological Results

API for using 'episensr', Basic sensitivity analysis of the observed relative risks adjusting for unmeasured confounding and misclassification of the exposure/outcome, or both. See < https://cran.r-project.org/package=episensr>.

Dynamic Linear Model for Wastewater-Based Epidemiology

Implement dynamic linear models outlined in Shumway and Stoffer (2025) . Two model structures for data smoothing and forecasting are considered. The specific models proposed will be added once the manuscript is published.

A Fast and Flexible Bayesian Tool for Estimating Epidemiological Parameters

Estimation of epidemiological parameters with Laplacian-P-splines following the methodology of Gressani et al. (2022) .