Random Coefficient Binary Response Estimation

Nonparametric maximum likelihood estimation methods for random coefficient binary response models and some related functionality for sequential processing of hyperplane arrangements. See J. Gu and R. Koenker (2020) .

Analysis of Factorial Experiments

Convenience functions for analyzing factorial experiments using ANOVA or mixed models. aov_ez(), aov_car(), and aov_4() allow specification of between, within (i.e., repeated-measures), or mixed (i.e., split-plot) ANOVAs for data in long format (i.e., one observation per row), automatically aggregating multiple observations per individual and cell of the design. mixed() fits mixed models using lme4::lmer() and computes p-values for all fixed effects using either Kenward-Roger or Satterthwaite approximation for degrees of freedom (LMM only), parametric bootstrap (LMMs and GLMMs), or likelihood ratio tests (LMMs and GLMMs). afex_plot() provides a high-level interface for interaction or one-way plots using ggplot2, combining raw data and model estimates. afex uses type 3 sums of squares as default (imitating commercial statistical software).

Simple Bootstrap Routines

Simple bootstrap routines.

Calculate Design Parameters for Biomarker Validation Studies

Helps a clinical trial team discuss the clinical goals of a well-defined biomarker with a diagnostic, staging, prognostic, or predictive purpose. From this discussion will come a statistical plan for a (non-randomized) validation trial. Both prospective and retrospective trials are supported. In a specific focused discussion, investigators should determine the range of "discomfort" for the NNT, number needed to treat. The meaning of the discomfort range, [NNTlower, NNTupper], is that within this range most physicians would feel discomfort either in treating or withholding treatment. A pair of NNT values bracketing that range, NNTpos and NNTneg, become the targets of the study's design. If the trial can demonstrate that a positive biomarker test yields an NNT less than NNTlower, and that a negative biomarker test yields an NNT less than NNTlower, then the biomarker may be useful for patients. A highlight of the package is visualization of a "contra-Bayes" theorem, which produces criteria for retrospective case-controls studies.

Enhanced Regression Nomogram Plot

A function to plot a regression nomogram of regression objects. Covariate distributions are superimposed on nomogram scales and the plot can be animated to allow on-the-fly changes to distribution representation and to enable outcome calculation.

Modeling and Plotting for Ecologist

It provides multiple functions that are useful for ecological research and teaching statistics to ecologists. It is based on data analysis courses offered at the Instituto de Ecología AC (INECOL). For references and published evidence see, Manrique-Ascencio, et al (2024) , Manrique-Ascencio et al (2024) , Ruiz-Guerra et al(2017) , Juarez-Fragoso et al (2024) , Papaqui-Bello et al (2024) .

Functions to Convert Between Weather Metrics

Functions to convert between weather metrics, including conversions for metrics of temperature, air moisture, wind speed, and precipitation. This package also includes functions to calculate the heat index from air temperature and air moisture.

File System Cache

Manages a file system cache. Regular files can be moved or copied to the cache folder. Sub-folders can be created in order to organize the files. Files can be located inside the cache using a glob function. Text contents can be easily stored in and retrieved from the cache using dedicated functions. It can be used for an application or a package, as a global cache, or as a per-user cache, in which case the standard OS user cache folder will be used (e.g.: on Linux $HOME/.cache/R/my_app_or_pkg_cache_folder).

Request Scheduler

Offers classes and functions to contact web servers while enforcing scheduling rules required by the sites. The URL class makes it easy to construct a URL by providing parameters as a vector. The Request class allows to describes SOAP (Simple Object Access Protocol) or standard requests: URL, method (POST or GET), header, body. The Scheduler class controls the request frequency for each server address by mean of rules (Rule class). The RequestResult class permits to get the request status to handle error cases and the content.

'SQL' Query Builder

Allows to build complex 'SQL' (Structured Query Language) queries dynamically. Classes and/or factory functions are used to produce a syntax tree from which the final character string is generated. Strings and identifiers are automatically quoted using the right quotes, using either ANSI (American National Standards Institute) quoting or the quoting style of an existing database connector. Style can be configured to set uppercase/lowercase for keywords, remove unnecessary spaces, or omit optional keywords.