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Omics Data Analysis
Similarity plots based on correlation and median absolute deviation (MAD); adjusting colors for heatmaps; aggregate technical replicates; calculate pairwise fold-changes and log fold-changes; compute one- and two-way ANOVA; simplified interface to package 'limma' (Ritchie et al. (2015),
Statistical Classification
Performance measures and scores for statistical classification such as accuracy, sensitivity, specificity, recall, similarity coefficients, AUC, GINI index, Brier score and many more. Calculation of optimal cut-offs and decision stumps (Iba and Langley (1991),
Estimators of Prediction Accuracy for Time-to-Event Data
Provides a variety of functions to estimate time-dependent true/false positive rates and AUC curves from a set of censored survival data.
Tools for Statistical Disclosure Control in Research Data Centers
Tools for researchers to explicitly show that their results comply to rules for statistical disclosure control imposed by research data centers. These tools help in checking descriptive statistics and models and in calculating extreme values that are not individual data. Also included is a simple function to create log files. The methods used here are described in the "Guidelines for the checking of output based on microdata research" by Bond, Brandt, and de Wolf (2015) < https://cros.ec.europa.eu/system/files/2024-02/Output-checking-guidelines.pdf>.
High Dimensional Categorical Data Visualization
Easy visualization for datasets with more than two categorical variables and additional continuous variables. 'diceplot' is particularly useful for exploring complex categorical data in the context of pathway analysis across multiple conditions. For a detailed documentation please visit < https://dice-and-domino-plot.readthedocs.io/en/latest/>.
Permutational Group Sequential Test for Time-to-Event Data
Permutational group-sequential tests for time-to-event data based on the log-rank test statistic. Supports exact permutation test when the censoring distributions are equal in the treatment and the control group and approximate imputation-permutation methods when the censoring distributions are different.
A Time Series Database for Official Statistics with R and PostgreSQL
Archive and manage times series data from official statistics. The 'timeseriesdb' package was designed to manage a large catalog of time series from official statistics which are typically published on a monthly, quarterly or yearly basis. Thus timeseriesdb is optimized to handle updates caused by data revision as well as elaborate, multi-lingual meta information.
Parametric Time-to-Event Analysis with Variable Incubation Phases
Fit parametric models for time-to-event data that show an initial 'incubation period', i.e., a variable delay phase where the hazard is zero. The delayed Weibull distribution serves as foundational data model. The specific method of 'MPSE' (maximum product of spacings estimation) and MLE-based methods are used for parameter estimation. Bootstrap confidence intervals for parameters and significance tests in a two group setting are provided.
Get Data from the 'KOF Datenservice' API
Read Swiss time series data from the 'KOF Data' API, < https://datenservice.kof.ethz.ch>. The API provides macro economic time series data mostly about Switzerland. The package itself is a set of wrappers around the 'KOF Datenservice' API. The 'kofdata' package is able to consume public information as well as data that requires an API token.
Article Formats for R Markdown
A suite of custom R Markdown formats and templates for authoring journal articles and conference submissions.