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SISIR — by Nathalie Villa-Vialaneix, 2 years ago

Sparse Interval Sliced Inverse Regression

An interval fusion procedure for functional data in the semiparametric framework of SIR. Standard ridge and sparse SIR are also included in the package.

SOMbrero — by Nathalie Villa-Vialaneix, a year ago

SOM Bound to Realize Euclidean and Relational Outputs

The stochastic (also called on-line) version of the Self-Organising Map (SOM) algorithm is provided. Different versions of the algorithm are implemented, for numeric and relational data and for contingency tables as described, respectively, in Kohonen (2001) , Olteanu & Villa-Vialaneix (2005) and Cottrell et al (2004) . The package also contains many plotting features (to help the user interpret the results) and a graphical user interface based on 'shiny'.

RNAseqNet — by Nathalie Villa-Vialaneix, 7 months ago

Log-Linear Poisson Graphical Model with Hot-Deck Multiple Imputation

Infer log-linear Poisson Graphical Model with an auxiliary data set. Hot-deck multiple imputation method is used to improve the reliability of the inference with an auxiliary dataset. Standard log-linear Poisson graphical model can also be used for the inference and the Stability Approach for Regularization Selection (StARS) is implemented to drive the selection of the regularization parameter. The method is fully described in .

ASICS — by GaĆ«lle Lefort, 7 months ago

Automatic Statistical Identification in Complex Spectra

With a set of pure metabolite spectra, ASICS quantifies metabolites concentration in a complex spectrum. The identification of metabolites is performed by fitting a mixture model to the spectra of the library with a sparse penalty. The method and its statistical properties are described in Tardivel et al. (2017) .

mixKernel — by Jerome Mariette, a year ago

Omics Data Integration Using Kernel Methods

Kernel-based methods are powerful methods for integrating heterogeneous types of data. mixKernel aims at providing methods to combine kernel for unsupervised exploratory analysis. Different solutions are provided to compute a meta-kernel, in a consensus way or in a way that best preserves the original topology of the data. mixKernel also integrates kernel PCA to visualize similarities between samples in a non linear space and from the multiple source point of view. Functions to assess and display important variables are also provided in the package.

adjclust — by Pierre Neuvial, 10 months ago

Adjacency-Constrained Clustering of a Block-Diagonal Similarity Matrix

Implements a constrained version of hierarchical agglomerative clustering, in which each observation is associated to a position, and only adjacent clusters can be merged. Typical application fields in bioinformatics include Genome-Wide Association Studies or Hi-C data analysis, where the similarity between items is a decreasing function of their genomic distance. Taking advantage of this feature, the implemented algorithm is time and memory efficient. This algorithm is described in Chapter 4 of Alia Dehman (2015) < https://hal.archives-ouvertes.fr/tel-01288568v1>.