Facilities for Simulating from ODE-Based Models

Facilities for running simulations from ordinary differential equation ('ODE') models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The 'VODE' and 'LSODA' are in the public domain. The information is available in the inst/COPYRIGHTS.


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Reference manual

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install.packages("RxODE")

1.1.1 by Wenping Wang, 24 days ago


https://nlmixrdevelopment.github.io/RxODE/, https://github.com/nlmixrdevelopment/RxODE/


Report a bug at https://github.com/nlmixrdevelopment/RxODE/issues/


Browse source code at https://github.com/cran/RxODE


Authors: Matthew L. Fidler [aut] , Melissa Hallow [aut] , Wenping Wang [aut, cre] , Zufar Mulyukov [ctb] , Alan Hindmarsh [ctb] , Awad H. Al-Mohy [ctb] , Matt Dowle [ctb] , Cleve Moler [ctb] , David Cooley [ctb] , Drew Schmidt [ctb] , Arun Srinivasan [ctb] , Ernst Hairer [ctb] , Gerhard Wanner [ctb] , Goro Fuji [ctb] , Hadley Wickham [ctb] , Jack Dongarra [ctb] , Linda Petzold [ctb] , Martin Maechler [ctb] , Matteo Fasiolo [ctb] , Morwenn [ctb] , Nicholas J. Higham [ctb] , Roger B. Sidje [ctb] , Simon Frost [ctb] , Kevin Ushey [ctb] , Yu Feng [ctb]


Documentation:   PDF Manual  


Task views: Differential Equations


GPL (>= 3) license


Imports PreciseSums, Rcpp, assertthat, backports, checkmate, cli, dparser, ggplot2, inline, lotri, magrittr, memoise, methods, rex, qs, sys, tools, utils

Suggests spelling, Matrix, DT, covr, crayon, curl, data.table, digest, dplyr, ggrepel, gridExtra, htmltools, knitr, learnr, microbenchmark, nlme, remotes, rlang, rmarkdown, scales, shiny, stringi, symengine, testthat, tidyr, usethis, vdiffr, xgxr, pillar, tibble, units, rsconnect, devtools, patchwork

Linking to dparser, PreciseSums, RcppEigen, RcppArmadillo, sitmo, StanHeaders, BH


Imported by nlmixr.


See at CRAN