Tidy Multilocus Amplicon Genotypes

Variant determination and genotyping from high throughput sequences from multilocus amplicon libraries, typically sequenced in Illumina MiSeq or similar. It provides a set of core functions for the central steps: demultiplex by locus, truncate reads, variant calling, and genotype calling. Additionally, it provides a set of functions for diagnosis and estimation of best running parameters and multiple extensions for genotype/variants manipulation and reformatting. Output variants and genotypes are output in 'tidy' format, thus facilitating reformatting, manipulation and potential connection to other R packages.

Nonparametric Spearman's Correlation for Survival Data

Nonparametric estimation of Spearman's rank correlation with bivariate survival (right-censored) data as described in Eden, S.K., Li, C., Shepherd B.E. (2021), Nonparametric Estimation of Spearman's Rank Correlation with Bivariate Survival Data, Biometrics (under revision). The package also provides functions that visualize bivariate survival data and bivariate probability mass function.

Kernel Machine Score Test for Semi-Competing Risks

Kernel Machine Score Test for Pathway Analysis in the Presence of Semi-Competing Risks. Method is detailed in: Neykov, Hejblum & Sinnott (2018) .

Calculate Pesticide Risk Metric (PRM) Values from Multiple Pesticides...Calc Them All

Contains functions which can be used to calculate Pesticide Risk Metric values in aquatic environments from concentrations of multiple pesticides with known species sensitive distributions (SSDs). Pesticides provided by this package have all be validated however if the user has their own pesticides with SSD values they can append them to the pesticide_info table to include them in estimates.

Multivariate Generalized Linear Mixed Models for Ranking Sports Teams

Maximum likelihood estimates are obtained via an EM algorithm with either a first-order or a fully exponential Laplace approximation as documented by Broatch and Karl (2018) , Karl, Yang, and Lohr (2014) , and by Karl (2012) . Karl and Zimmerman use this package to illustrate how the home field effect estimator from a mixed model can be biased under nonrandom scheduling.

Semi-Parametric Shape-Restricted Fixed/Mixed Effect(s) Regression Spline

Select the most suitable shape to describe the relationship between the exposure and the outcome among increasing, decreasing, convex, and concave shapes (Yin et al. (2021) ); estimate the direct and indirect effects with prior knowledge on the relationship between the mediator and the outcome with binary exposure (Yin et al. (2024) ); estimate the direct and indirect effects using linear regression-based approach (VanderWeele (2015, ISBN:9780199325870)).

Minimal Type Guesser

Port the type guesser from 'readr' (so-called 'readr' first edition parsing engine, now superseded by 'vroom').

Mark-Recapture Analysis

Accomplishes mark-recapture analysis with covariates. Models available include the Cormack-Jolly-Seber open population (Cormack (1972) ; Jolly (1965) ; Seber (1965) ) and Huggin's (1989) closed population. Link functions include logit, sine, and hazard. Model selection, model averaging, plot, and simulation routines included. Open population size by the Horvitz-Thompson (1959) estimator.

Working with Sets the Tidy Way

Implements a class and methods to work with sets, doing intersection, union, complementary sets, power sets, cartesian product and other set operations in a "tidy" way. These set operations are available for both classical sets and fuzzy sets. Import sets from several formats or from other several data structures.

'Rcpp' Bindings for 'Redis' using the 'hiredis' Library

Connection to the 'Redis' (or 'Valkey') key/value store using the C-language client library 'hiredis' (included as a fallback) with 'MsgPack' encoding provided via 'RcppMsgPack' headers. It now also includes the pub/sub functions from the 'rredis' package.