Two-Sample Test of many Functional Means using the Energy Method

Given two samples of size n_1 and n_2 from a data set where each sample consists of K functional observations (channels), each recorded on T grid points, the function energy method implements a hypothesis test of equality of channel-wise mean at each channel using the bootstrapped distribution of maximum energy to control family wise error. The function energy_method_complex accomodates complex valued functional observations.

Optimization via Subsampling (OPTS)

Subsampling based variable selection for low dimensional generalized linear models. The methods repeatedly subsample the data minimizing an information criterion (AIC/BIC) over a sequence of nested models for each subsample. Marinela Capanu, Mihai Giurcanu, Colin B Begg, Mithat Gonen, Subsampling based variable selection for generalized linear models.

String Diff, Match, and Patch Utilities

A wrapper for Google's 'diff-match-patch' library. It provides basic tools for computing diffs, finding fuzzy matches, and constructing / applying patches to strings.

Multi-Barrier Approach for Water Reuse Risk Assessment

Provides a Quantitative Microbial Risk Assessment (QMRA) framework for the reuse of treated wastewater in agricultural irrigation. Following a multi-barrier approach, the package simulates pathogen inflow and removal along a treatment train, estimates human exposure, and computes health risk indicators such as infection probability, illness probability, and Disability-Adjusted Life Years (DALYs). It also supports an economic analysis of the treatment scenarios considered. For more details see .

R Interface to the Pushbullet Messaging Service

An R interface to the Pushbullet messaging service which provides fast and efficient notifications (and file transfer) between computers, phones and tablets. An account has to be registered at the site < https://www.pushbullet.com> site to obtain a (free) API key.

Fits a Fay Herriot Model

Inference techniques for Fay Herriot Model.

Selection Threshold Optimized Empirically via Splitting

Implements variable selection procedures for low to moderate size generalized linear regressions models. It includes the STOPES functions for linear regression (Capanu M, Giurcanu M, Begg C, Gonen M, Optimized variable selection via repeated data splitting, Statistics in Medicine, 2020, 19(6):2167-2184) as well as subsampling based optimization methods for generalized linear regression models (Marinela Capanu, Mihai Giurcanu, Colin B Begg, Mithat Gonen, Subsampling based variable selection for generalized linear models).

A Hypothesis Testing Framework for Validating an Assay for Precision

A common way of validating a biological assay for is through a procedure, where m levels of an analyte are measured with n replicates at each level, and if all m estimates of the coefficient of variation (CV) are less than some prespecified level, then the assay is declared validated for precision within the range of the m analyte levels. Two limitations of this procedure are: there is no clear statistical statement of precision upon passing, and it is unclear how to modify the procedure for assays with constant standard deviation. We provide tools to convert such a procedure into a set of m hypothesis tests. This reframing motivates the m:n:q procedure, which upon completion delivers a 100q% upper confidence limit on the CV. Additionally, for a post-validation assay output of y, the method gives an ``effective standard deviation interval'' of log(y) plus or minus r, which is a 68% confidence interval on log(mu), where mu is the expected value of the assay output for that sample. Further, the m:n:q procedure can be straightforwardly applied to constant standard deviation assays. We illustrate these tools by applying them to a growth inhibition assay. This is an implementation of the methods described in Fay, Sachs, and Miura (2018) .

Reliably Return the Source and Call Location of a Command

Robust and reliable functions to return informative outputs to console with the run or source location of a command. This can be from the 'RScript'/R terminal commands or 'RStudio' console, source editor, 'Rmarkdown' document and a Shiny application.

Tools for Managing Classes on GitHub

Interface for the GitHub API that enables efficient management of courses on GitHub. It has a functionality for managing organizations, teams, repositories, and users on GitHub and helps automate most of the tedious and repetitive tasks around creating and distributing assignments.